英国: 流感疫苗加速安检 - 望5天内完成，9月上市

awake

http://www.timesonline.co.uk/tol ... /article6694046.ece
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Swine flu vaccine rushed through safety checks

! a. j6 c7 D" ]) n* lA vaccine against swine flu will be fast-tracked for use in Britain in just five days, with 130 million doses on order.

The Department of Health expects to have enough vaccine to give it to half the population this year and, should enough people want it, vaccinations for the remainder over a longer period. Each person will need two doses of the vaccine.
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- R  Z7 |( f4 q$ u+ xThe first doses specific to the H1N1 swine flu virus are due to arrive in September and could be prioritised through regulatory approval in less than a week.
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# g0 F$ J8 X, d* T& EIt comes after the first British patient without underlying health problems died after contracting swine flu, taking the number of swine flu-linked deaths in Britain to 15.
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2 D# u$ J( w6 `0 e- qPeter Holden, the British Medical Association’s lead negotiator on swine flu, who has been attending Department of Health meetings on the outbreak, said that GPs’ surgeries were prepared for one of the biggest winter vaccination campaigns in almost 50 years.

He said that, although swine flu was not causing serious illness in patients, health officials were eager to start a mass vaccination campaign, starting with priority groups who were susceptible to infection or prone to complications.
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+ H& l# S# m4 g* d2 `, ?1 s$ aIt is likely that the elderly would be given a seasonal flu jab to guard against other strains — as happens every year — as well as the swine flu vaccination, Dr Holden said. The new vaccine is likely to be given in two doses but it could be left as a single jab if this is found to provide high rates of immunity.

. k( G* H, C: d4 y"The high-risk groups will be done at GPs’ surgeries. People are still making decisions over this, but we want to get cracking before we get a second wave, which is traditionally far more virulent,” he said.
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Britain has a stockpile of 500 million doses of Tamiflu (ostelamivir), the anti-viral drug used to treat flu symptoms. A vaccine however would provide a preventative measure against illness and would be used to ease pressure on the health service and the wider economy if several million people become ill, as expected at the height of a pandemic.

It takes several weeks or months to make flu vaccines because they have to be cultured using chicken eggs.

: Y* W0 v2 ^& x& k0 E; O5 zRegulators at the European Medicines Agency (EMEA) said that the fast-tracked procedure has involved clinical trials of a “mock-up” vaccine similar to the one that will be used for the biggest mass vaccination programme in generations. It will be introduced into the general population while regulators continue to carry out simultaneous clinical trials.

The EMEA said that fast-tracking would not be at the expense of patient safety, adding: “The vaccines are authorised with a detailed risk management plan. There is quite a body of evidence regarding safety on the trials of the mock-up, and the actual vaccine could be assessed in five days.”

/ m. y# V1 I' @6 v, q' PThe Department of Health said that a vaccination programme would be drawn up based on expert advice.

awake

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英国第15例阵亡病人，确认患流感前无其它健康问题。

- n# N! d2 ]) m7 p0 d这一病例促使疫苗的安检/批准流程加速，望9月可供市场。 现订单量已达一亿支，预计每人需要两支疫苗。计划年内覆盖一半英国人口。

whst111

英国动作很快啊. 不知这疫苗是否经过生物测试??????????

vilna

英国动作很快啊. 不知这疫苗是否经过生物测试??????????
whst111 发表于 2009-7-12 22:27

那是一定的。
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疫苗都有少数人会不适应，比如会诱发一种格林巴氏综合征，但比例极小，大概是百万人口分之几。